Systems Biology Approaches to Disease Marker Discovery
Our understanding of human disease and potential therapeutics is improving rapidly. In order to take advantage of these developments it is important to be able to identify disease markers. Many new high-throughput genomics and proteomics technologies are being implemented to identify candidate disea...
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| Format: | Online |
| Language: | English |
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IOS Press
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833409/ |
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pubmed-3833409 |
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pubmed-38334092013-12-17 Systems Biology Approaches to Disease Marker Discovery Sharon, Donald Chen, Rui Snyder, Michael Other Our understanding of human disease and potential therapeutics is improving rapidly. In order to take advantage of these developments it is important to be able to identify disease markers. Many new high-throughput genomics and proteomics technologies are being implemented to identify candidate disease markers. These technologies include protein microarrays, next-generation DNA sequencing and mass spectrometry platforms. Such methods are particularly important for elucidating the repertoire of molecular markers in the genome, transcriptome, proteome and metabolome of patients with diseases such as cancer, autoimmune diseases, and viral infections, resulting from the disruption of many biological pathways. These new technologies have identified many potential disease markers. These markers are expected to be valuable to achieve the promise of truly personalized medicine. IOS Press 2010 2010-06-09 /pmc/articles/PMC3833409/ /pubmed/20534906 http://dx.doi.org/10.3233/DMA-2010-0707 Text en Copyright © 2010 Hindawi Publishing Corporation. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Sharon, Donald Chen, Rui Snyder, Michael |
| spellingShingle |
Sharon, Donald Chen, Rui Snyder, Michael Systems Biology Approaches to Disease Marker Discovery |
| author_facet |
Sharon, Donald Chen, Rui Snyder, Michael |
| author_sort |
Sharon, Donald |
| title |
Systems Biology Approaches to Disease Marker Discovery |
| title_short |
Systems Biology Approaches to Disease Marker Discovery |
| title_full |
Systems Biology Approaches to Disease Marker Discovery |
| title_fullStr |
Systems Biology Approaches to Disease Marker Discovery |
| title_full_unstemmed |
Systems Biology Approaches to Disease Marker Discovery |
| title_sort |
systems biology approaches to disease marker discovery |
| description |
Our understanding of human disease and potential therapeutics is improving rapidly. In order to take advantage of these developments it is important to be able to identify disease markers. Many new high-throughput genomics and proteomics technologies are being implemented to identify candidate disease markers. These technologies include protein microarrays, next-generation DNA sequencing and mass spectrometry platforms. Such methods are particularly important for elucidating the repertoire of molecular markers in the genome, transcriptome, proteome and metabolome of patients with diseases such as cancer, autoimmune diseases, and viral infections, resulting from the disruption of many biological pathways. These new technologies have identified many potential disease markers. These markers are expected to be valuable to achieve the promise of truly personalized medicine. |
| publisher |
IOS Press |
| publishDate |
2010 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833409/ |
| _version_ |
1612028456601649152 |