Systems biology approaches for advancing the discovery of effective drug combinations

Complex diseases like cancer are regulated by large, interconnected networks with many pathways affecting cell proliferation, invasion, and drug resistance. However, current cancer therapy predominantly relies on the reductionist approach of one gene-one disease. Combinations of drugs may overcome d...

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Bibliographic Details
Main Authors: Ryall, Karen A, Tan, Aik Choon
Format: Online
Language:English
Published: Springer International Publishing 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348553/