Platelet P2Y12 Is Involved in Murine Pulmonary Metastasis

The involvement of platelets in tumor progression is well recognized. The depletion of circulating platelets or pharmacologic inhibitors of platelet activation decreases the metastatic potential of circulating tumor cells in metastasis mouse models. The platelet ADP receptor P2Y12 amplifies the init...

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Bibliographic Details
Main Authors: Wang, Yanhua, Sun, Yueping, Li, Ding, Zhang, Lin, Wang, Kemin, Zuo, Yong, Gartner, T. Kent, Liu, Junling
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827483/