Integrin αIIb-Mediated PI3K/Akt Activation in Platelets

Integrin αIIb-Mediated PI3K/Akt Activation in Platelets

Integrin αIIbβ3 mediated bidirectional signaling plays a critical role in thrombosis and haemostasis. Signaling mediated by the β3 subunit has been extensively studied, but αIIb mediated signaling has not been characterized. Previously, we reported that platelet granule secretion and TxA2 production...

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Bibliographic Details
Main Authors: Niu, Haixia, Chen, Xue, Gruppo, Ralph A., Li, Ding, Wang, Yanhua, Zhang, Lin, Wang, Kemin, Chai, Weiran, Sun, Yueping, Ding, Zhongren, Gartner, T. Kent, Liu, Junling
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474815/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474815/

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