EGFR-Ras-Raf Signaling in Epidermal Stem Cells: Roles in Hair Follicle Development, Regeneration, Tissue Remodeling and Epidermal Cancers
The mammalian skin is the largest organ of the body and its outermost layer, the epidermis, undergoes dynamic lifetime renewal through the activity of somatic stem cell populations. The EGFR-Ras-Raf pathway has a well-described role in skin development and tumor formation. While research mainly focu...
Main Authors: | Doma, Eszter, Rupp, Christian, Baccarini, Manuela |
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Format: | Online |
Language: | English |
Published: |
Molecular Diversity Preservation International (MDPI)
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821561/ |
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