“RAF” neighborhood: Protein–protein interaction in the Raf/Mek/Erk pathway

The Raf/Mek/Erk signaling pathway, activated downstream of Ras primarily to promote proliferation, represents the best studied of the evolutionary conserved MAPK cascades. The investigation of the pathway has continued unabated since its discovery roughly 30 years ago. In the last decade, however, t...

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Bibliographic Details
Main Authors: Cseh, Botond, Doma, Eszter, Baccarini, Manuela
Format: Online
Language:English
Published: Elsevier Science B.V 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099524/