HLA ligandome tumor antigen discovery for personalized vaccine approach
Every cancer is different and cancer cells differ from normal cells, in particular, through genetic alterations. HLA molecules on the cell surface enable T lymphocytes to recognize cellular alterations as antigens, including mutations, increase in gene product copy numbers or expression of genes usu...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Informa Healthcare
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821395/ |