Proprotein Convertase Subtilisin/Kexin Type 9: From the Discovery to the Development of New Therapies for Cardiovascular Diseases
The identification of the HMG-CoA reductase inhibitors, statins, has represented a dramatic innovation of the pharmacological modulation of hypercholesterolemia and associated cardiovascular diseases. However, not all patients receiving statins achieve guideline-recommended low density lipoprotein (...
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Format: | Online |
Language: | English |
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Hindawi Publishing Corporation
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820617/ |