Development of a general methodology for labelling peptide–morpholino oligonucleotide conjugates using alkyne–azide click chemistry† †Electronic supplementary information (ESI) available: Experimental section and supplementary figures. See DOI: 10.1039/c3cc46067c Click here for additional data file.

A general and convenient solid-phase synthesis method using Cu(i)-mediated alkyne–azide click chemistry for attachment of an azide derivative of a fluorescent label to an alkyne derivative of a peptide conjugated to a morpholino oligonucleotide (PMO).

Bibliographic Details
Main Authors: Shabanpoor, Fazel, Gait, Michael J.
Format: Online
Language:English
Published: Royal Society of Chemistry 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816334/