Inference of Gene-Phenotype Associations via Protein-Protein Interaction and Orthology

One of the fundamental goals of genetics is to understand gene functions and their associated phenotypes. To achieve this goal, in this study we developed a computational algorithm that uses orthology and protein-protein interaction information to infer gene-phenotype associations for multiple speci...

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Bibliographic Details
Main Authors: Wang, Panwen, Lai, Wing-Fu, Li, Mulin Jun, Xu, Feng, Yalamanchili, Hari Krishna, Lovell-Badge, Robin, Wang, Junwen
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806783/