SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples

Conventionally, overall gene expressions from microarrays are used to infer gene networks, but it is challenging to account splicing isoforms. High-throughput RNA Sequencing has made splice variant profiling practical. However, its true merit in quantifying splicing isoforms and isoform-specific exo...

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Bibliographic Details
Main Authors: Yalamanchili, Hari Krishna, Li, Zhaoyuan, Wang, Panwen, Wong, Maria P., Yao, Jianfeng, Wang, Junwen
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150760/