Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

Aging strongly promotes inflammation responses, which may predispose individuals after cancer therapies to lethal system toxicities and pathology that can be partially prevented by TNF blockade.

Bibliographic Details
Main Authors: Bouchlaka, Myriam N., Sckisel, Gail D., Chen, Mingyi, Mirsoian, Annie, Zamora, Anthony E., Maverakis, Emanual, Wilkins, Danice E.C., Alderson, Kory L., Hsiao, Hui-Hua, Weiss, Jonathan M., Monjazeb, Arta M., Hesdorffer, Charles, Ferrucci, Luigi, Longo, Dan L., Blazar, Bruce R., Wiltrout, Robert H., Redelman, Doug, Taub, Dennis D., Murphy, William J.
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804937/