The Tumor Suppressor Gene, RASSF1A, Is Essential for Protection against Inflammation -Induced Injury

The Tumor Suppressor Gene, RASSF1A, Is Essential for Protection against Inflammation -Induced Injury

Ras association domain family protein 1A (RASSF1A) is a tumor suppressor gene silenced in cancer. Here we report that RASSF1A is a novel regulator of intestinal inflammation as Rassf1a+/−, Rassf1a−/− and an intestinal epithelial cell specific knockout mouse (Rassf1a IEC-KO) rapidly became sick follo...

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Bibliographic Details
Main Authors: Gordon, Marilyn, El-Kalla, Mohamed, Zhao, Yuewen, Fiteih, Yahya, Law, Jennifer, Volodko, Natalia, Mohamed, Anwar, El-Kadi, Ayman O. S., Liu, Lei, Odenbach, Jeff, Thiesen, Aducio, Onyskiw, Christina, Ghazaleh, Haya Abu, Park, Jikyoung, Lee, Sean Bong, Yu, Victor C., Fernandez-Patron, Carlos, Alexander, R. Todd, Wine, Eytan, Baksh, Shairaz
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797720/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797720/

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