RASSF1A Site-Specific Methylation Hotspots in Cancer and Correlation with RASSF1C and MOAP-1

Epigenetic silencing of RASSF1A is frequently observed in numerous cancers and has been previously reported. The promoter region of RASSF1A is predicted to have 75 CpG sites, and very few studies demonstrate how the methylation of these sites affects expression. In addition, the expression relations...

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Bibliographic Details
Main Authors: Volodko, Natalia, Salla, Mohamed, Zare, Alaa, Abulghasem, El-Arbi, Vincent, Krista, Benesch, Matthew G.K., McMullen, Todd P.W., Bathe, Oliver F., Postovit, Lynne, Baksh, Shairaz
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931620/