Overexpression of DRAM enhances p53-dependent apoptosis
Tumor suppressor p53-dependent apoptosis is thought to be one of the most important tumor-suppressive mechanisms in human tumorigenesis. Till date, “super p53” mutants exhibiting more potent ability to induce apoptosis than wild-type p53 have been reported. These super p53s may provide a clue for de...
Main Authors: | Takahashi, Masahiro, Kakudo, Yuichi, Takahashi, Shin, Sakamoto, Yasuhiro, Kato, Shunsuke, Ishioka, Chikashi |
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Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Ltd
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797565/ |
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