Overexpression of DRAM enhances p53-dependent apoptosis

Tumor suppressor p53-dependent apoptosis is thought to be one of the most important tumor-suppressive mechanisms in human tumorigenesis. Till date, “super p53” mutants exhibiting more potent ability to induce apoptosis than wild-type p53 have been reported. These super p53s may provide a clue for de...

Full description

Bibliographic Details
Main Authors: Takahashi, Masahiro, Kakudo, Yuichi, Takahashi, Shin, Sakamoto, Yasuhiro, Kato, Shunsuke, Ishioka, Chikashi
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797565/