Indole prevents Escherichia coli cell division by modulating membrane potential

Indole is a bacterial signalling molecule that blocks E. coli cell division at concentrations of 3–5 mM. We have shown that indole is a proton ionophore and that this activity is key to the inhibition of division. By reducing the electrochemical potential across the cytoplasmic membrane of E. coli,...

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Bibliographic Details
Main Authors: Chimerel, Catalin, Field, Christopher M., Piñero-Fernandez, Silvia, Keyser, Ulrich F., Summers, David K.
Format: Online
Language:English
Published: Elsevier Pub. Co 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793866/