Sonic Hedgehog Regulates Osteoblast Function by Focal Adhesion Kinase Signaling in the Process of Fracture Healing

Sonic Hedgehog Regulates Osteoblast Function by Focal Adhesion Kinase Signaling in the Process of Fracture Healing

Several biological studies have indicated that hedgehog signaling plays an important role in osteoblast proliferation and differentiation, and sonic hedgehog (SHH) expression is positively correlated with phosphorylated focal adhesion kinase (FAK) Tyr397. However, the relationship between them and t...

Full description

Bibliographic Details
Main Authors:	Horikiri, Yuu, Shimo, Tsuyoshi, Kurio, Naito, Okui, Tatsuo, Matsumoto, Kenichi, Iwamoto, Masahiro, Sasaki, Akira
Format:	Online
Language:	English
Published:	Public Library of Science 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790742/

Similar Items

The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction
by: Shimo, Tsuyoshi, et al.
Published: (2016)

Sonic Hedgehog in SCLC
by: Laukkanen, Mikko O., et al.
Published: (2015)

Osteoblast-secreted collagen upregulates paracrine Sonic hedgehog signaling by prostate cancer cells and enhances osteoblast differentiation
by: Zunich, Samantha M, et al.
Published: (2012)

Inhibitors of Hedgehog Acyltransferase Block Sonic Hedgehog Signaling
by: Petrova, Elissaveta, et al.
Published: (2013)

Regulation of Thalamic Development by Sonic Hedgehog
by: Epstein, Douglas J.
Published: (2012)

A highlight on Sonic hedgehog pathway
by: Gabriela Basile Carballo, et al.
Published: (2018-03-01)

Probing extracellular Sonic hedgehog in neurons
by: Eitan, Erez, et al.
Published: (2016)

Sonic Hedgehog regulates thymic epithelial cell differentiation
by: Saldaña, José Ignacio, et al.
Published: (2016)

Fibronectin modified expression of Sonic hedgehog in ATRA-mediated neuronal differentiation
by: ARAHARA, Kazuhiko, et al.
Published: (2015)

Sonic Hedgehog Opposes Epithelial Cell Cycle Arrest
by: Fan, Hongran, et al.
Published: (1999)

Developmental pathways: Sonic hedgehog-Patched-GLI.
by: Walterhouse, D O, et al.
Published: (1999)

Sonic hedgehog promotes autophagy in hippocampal neurons
by: Petralia, Ronald S., et al.
Published: (2013)

Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway
by: Schaefer, Giannina I., et al.
Published: (2013)

Characterization of sonic hedgehog inhibition in gastric carcinoma cells
by: BAI, RUXUE, et al.
Published: (2014)

Sonic Hedgehog factor Gli1: As good as resistant
by: Zahreddine, Hiba Ahmad, et al.
Published: (2015)

Sonic Hedgehog: a lipid speciated hormone?
by: Long, Jun, et al.
Published: (2015)

Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma
by: Jenkins, Noah C, et al.
Published: (2014)

Mesencephalic basolateral domain specification is dependent on Sonic Hedgehog
by: Martinez-Lopez, Jesus E., et al.
Published: (2015)

Sonic hedgehog signaling in the development of the mouse hypothalamus
by: Blaess, Sandra, et al.
Published: (2015)

Sonic hedgehog signalling pathway: a complex network
by: Choudhry, Zia, et al.
Published: (2014)

Effect of sonic hedgehog/β-TCP composites on bone healing within the critical-sized rat femoral defect
by: WARZECHA, JÖRG, et al.
Published: (2013)

Is Sonic Hedgehog Involved in Human Fracture Healing? - A Prospective Study on Local and Systemic Concentrations of SHH
by: Eipeldauer, Stefan, et al.
Published: (2014)

Sonic hedgehog lineage in the mouse hypothalamus: from progenitor domains to hypothalamic regions
by: Alvarez-Bolado, Gonzalo, et al.
Published: (2012)

Transient Overexpression of Sonic Hedgehog Alters the Architecture and Mechanical Properties of Trabecular Bone
by: Kiuru, Maija, et al.
Published: (2009)

Using mechanistic Bayesian networks to identify downstream targets of the Sonic Hedgehog pathway
by: Shah, Abhik, et al.
Published: (2009)

Lipid Modifications of Sonic Hedgehog Ligand Dictate Cellular Reception and Signal Response
by: Grover, Vandana K., et al.
Published: (2011)

Targeting Sonic Hedgehog Signaling by Compounds and Derivatives from Natural Products
by: Huang, Yu-Chuen, et al.
Published: (2013)

Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance
by: Avilés, Evelyn C., et al.
Published: (2013)

Controlled Delivery of Sonic Hedgehog Morphogen and Its Potential for Cardiac Repair
by: Johnson, Noah Ray, et al.
Published: (2013)

The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling
by: Khonsari, Roman H, et al.
Published: (2013)

Sonic hedgehog promotes generation and maintenance of human forebrain Olig2 progenitors
by: Ortega, J. Alberto, et al.
Published: (2013)

Anti-apoptotic role of the sonic hedgehog signaling pathway in the proliferation of ameloblastoma
by: KANDA, SHIORI, et al.
Published: (2013)

Sonic Hedgehog Protein Is Decreased and Penile Morphology Is Altered in Prostatectomy and Diabetic Patients
by: Angeloni, Nicholas L., et al.
Published: (2013)

Sonic Hedgehog Mediates the Proliferation and Recruitment of Transformed Mesenchymal Stem Cells to the Stomach
by: Donnelly, Jessica M., et al.
Published: (2013)

Analysis of the Sonic Hedgehog Signaling Pathway in Normal and Abnormal Bladder Development
by: DeSouza, Kristin R., et al.
Published: (2013)

Novel Sonic Hedgehog Mutation in a Couple with Variable Expression of Holoprosencephaly
by: Aguinaga, M., et al.
Published: (2011)

Sonic Hedgehog Improves Redifferentiation of Dedifferentiated Chondrocytes for Articular Cartilage Repair
by: Lin, Lin, et al.
Published: (2014)

Sonic Hedgehog Pathway Contributes to Gastric Cancer Cell Growth and Proliferation
by: Wan, Jianhua, et al.
Published: (2014)

Loss of Sonic Hedgehog Leads to Alterations in Intestinal Secretory Cell Maturation and Autophagy
by: Gagné-Sansfaçon, Jessica, et al.
Published: (2014)

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception
by: Yue, Shen, et al.
Published: (2014)