The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction

Sonic hedgehog (SHH) and its signaling have been identified in several human cancers, and increased levels of its expression appear to correlate with disease progression and metastasis. However, the role of SHH in bone destruction associated with oral squamous cell carcinomas is still unclear. In th...

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Bibliographic Details
Main Authors: Shimo, Tsuyoshi, Matsumoto, Kenichi, Takabatake, Kiyofumi, Aoyama, Eriko, Takebe, Yuichiro, Ibaragi, Soichiro, Okui, Tatsuo, Kurio, Naito, Takada, Hiroyuki, Obata, Kyoichi, Pang, Pai, Iwamoto, Masahiro, Nagatsuka, Hitoshi, Sasaki, Akira
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805186/