Epigenetic regulation of the human telomerase reverse transciptase gene: A potential therapeutic target for the treatment of leukemia (Review)

Telomerase activation is a critical step in human carcinogenesis through the maintenance of telomeres. Telomerase activity is primarily regulated by the human telomerase reverse transcriptase gene (hTERT), thus, an improved understanding of the transcriptional control of hTERT may provide potential...

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Bibliographic Details
Main Authors: SUI, XINBING, KONG, NA, WANG, ZHANGGUI, PAN, HONGMING
Format: Online
Language:English
Published: D.A. Spandidos 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789043/