Characterizing the Role of Brain Derived Neurotrophic Factor Genetic Variation in Alzheimer’s Disease Neurodegeneration

There is accumulating evidence that neurotrophins, like brain-derived neurotrophic factor (BDNF), may impact aging and Alzheimer’s Disease. However, traditional genetic association studies have not found a clear relationship between BDNF and AD. Our goal was to test whether BDNF single nucleotide po...

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Bibliographic Details
Main Authors: Honea, Robyn A., Cruchaga, Carlos, Perea, Rodrigo D., Saykin, Andrew J., Burns, Jeffrey M., Weinberger, Daniel R., Goate, Alison M.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784423/