Focused ultrasound-enhanced intranasal brain delivery of brain-derived neurotrophic factor

The objective of this study was to unveil the potential mechanism of focused ultrasound (FUS)-enhanced intranasal (IN) brain drug delivery and assess its feasibility in the delivery of therapeutic molecules. Delivery outcomes of fluorescently-labeled dextrans to mouse brains by IN administration eit...

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Bibliographic Details
Main Authors: Chen, Hong, Yang, Georgiana Zong Xin, Getachew, Hoheteberhan, Acosta, Camilo, Sierra Sánchez, Carlos, Konofagou, Elisa E.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921840/