Action potential wavelength restitution predicts alternans and arrhythmia in murine Scn5a+/− hearts
Reductions in cardiac action potential wavelength, and the consequent wavebreak, have been implicated in arrhythmogenesis. Tachyarrhythmias are more common in the Brugada syndrome, particularly following pharmacological challenge, previously modelled using Scn5a+/− murine hearts. Propagation latenci...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Blackwell Science Inc
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779110/ |