Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission
This study demonstrates a novel and unexpected role in cytokinesis for leukemia-associated RhoGEF (LARG). Depletion of LARG results in delayed abscission, and thus LARG is the first RhoGEF to be implicated in late cytokinesis.
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771942/ |
| Summary: | This study demonstrates a novel and unexpected role in cytokinesis for leukemia-associated RhoGEF (LARG). Depletion of LARG results in delayed abscission, and thus LARG is the first RhoGEF to be implicated in late cytokinesis. |
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