Tissue absence initiates regeneration through Follistatin-mediated inhibition of Activin signaling

Regeneration is widespread, but mechanisms that activate regeneration remain mysterious. Planarians are capable of whole-body regeneration and mount distinct molecular responses to wounds that result in tissue absence and those that do not. A major question is how these distinct responses are activa...

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Bibliographic Details
Main Authors: Gaviño, Michael A, Wenemoser, Danielle, Wang, Irving E, Reddien, Peter W
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771573/