Human testicular germ cell tumours express inhibin subunits, activin receptors and follistatin mRNAs.

Germ cell development is influenced by activin and inhibin, which are produced by Sertoli cells. Activin also affects differentiation of mouse embryonal carcinoma cells, which, to a certain extent, resemble the embryonal carcinoma component of germ cell tumours. Therefore, the expression of inhibin/...

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Bibliographic Details
Main Authors: van Schaik, R. H., Wierikx, C. D., Looijenga, L. H., Oosterhuis, J. W., de Jong, F. H.
Format: Online
Language:English
Published: Nature Publishing Group 1997
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228115/