Role of Presynaptic Glutamate Receptors in Pain Transmission at the Spinal Cord Level
Nociceptive primary afferents release glutamate, activating postsynaptic glutamate receptors on spinal cord dorsal horn neurons. Glutamate receptors, both ionotropic and metabotropic, are also expressed on presynaptic terminals, where they regulate neurotransmitter release. During the last two decad...
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| Format: | Online |
| Language: | English |
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Bentham Science Publishers
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763755/ |