Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys

Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys

In contrast to pathogenic HIV/SIV infections of humans and rhesus macaques (RMs), natural SIV infection of sooty mangabeys (SMs) is typically non-pathogenic despite high viremia. Several studies suggested that low immune activation and relative resistance of CD4+ central memory T-cells from virus in...

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Main Authors: Bosinger, Steven E., Johnson, Zachary P., Folkner, Kathryn A., Patel, Nirav, Hashempour, Tayebeh, Jochems, Simon P., del Rio Estrada, Perla M., Paiardini, Mirko, Lin, Rongtuan, Vanderford, Thomas H., Hiscott, John, Silvestri, Guido
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757038/

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