Regulated Intramembrane Proteolysis and Degradation of Murine Epithelial Cell Adhesion Molecule mEpCAM

Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein, which is highly and frequently expressed in carcinomas and (cancer-)stem cells, and which plays an important role in the regulation of stem cell pluripotency. We show here that murine EpCAM (mEpCAM) is subject to regulated intr...

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Bibliographic Details
Main Authors: Hachmeister, Matthias, Bobowski, Karolina D., Hogl, Sebastian, Dislich, Bastian, Fukumori, Akio, Eggert, Carola, Mack, Brigitte, Kremling, Heidi, Sarrach, Sannia, Coscia, Fabian, Zimmermann, Wolfgang, Steiner, Harald, Lichtenthaler, Stefan F., Gires, Olivier
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756971/