Q/R site interactions with the M3 helix in GluK2 kainate receptor channels revealed by thermodynamic mutant cycles
RNA editing at the Q/R site near the apex of the pore loop of AMPA and kainate receptors controls a diverse array of channel properties, including ion selectivity and unitary conductance and susceptibility to inhibition by polyamines and cis-unsaturated fatty acids, as well as subunit assembly into...
Main Authors: | Lopez, Melany N., Wilding, Timothy J., Huettner, James E. |
---|---|
Format: | Online |
Language: | English |
Published: |
The Rockefeller University Press
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753602/ |
Similar Items
-
Parkin regulates kainate receptors by interacting with the GluK2 subunit
by: Maraschi, AnnaMaria, et al.
Published: (2014) -
Expression of GluK1c underlies the developmental switch in presynaptic kainate receptor function
by: Vesikansa, Aino, et al.
Published: (2012) -
SUMOylation and phosphorylation of GluK2 regulate kainate receptor trafficking and synaptic plasticity
by: Chamberlain, Sophie E L, et al.
Published: (2012) -
Modification and movement: Phosphorylation and SUMOylation regulate endocytosis of GluK2-containing kainate receptors
by: Wilkinson, Kevin A., et al.
Published: (2012) -
A Study of GluK1 Kainate Receptor Polymorphisms in Down Syndrome Reveals Allelic Non-Disjunction at 1173(C/T)
by: Ghosh, Debarati, et al.
Published: (2009)