Radial Symmetry in a Chimaeric Glutamate Receptor Pore
Ionotropic glutamate receptors comprise two conformationally different A/C and B/D subunit pairs. Closed channels exhibit 4-fold radial symmetry in the transmembrane domain (TMD) but transition to 2-fold dimer-of-dimers symmetry for extracellular ligand binding and N-terminal domains. Here, to evalu...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962659/ |