Ex-Vivo Dynamic 3-D Culture of Human Tissues in the RCCS™ Bioreactor Allows the Study of Multiple Myeloma Biology and Response to Therapy

Three-dimensional (3-D) culture models are emerging as invaluable tools in tumor biology, since they reproduce tissue-specific structural features and cell-cell interactions more accurately than conventional 2-D cultures. Multiple Myeloma, which depends on myeloma cell-Bone Marrow microenvironment i...

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Bibliographic Details
Main Authors: Ferrarini, Marina, Steimberg, Nathalie, Ponzoni, Maurilio, Belloni, Daniela, Berenzi, Angiola, Girlanda, Stefania, Caligaris-Cappio, Federico, Mazzoleni, Giovanna, Ferrero, Elisabetta
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753321/