The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway
The incretin hormone glucagon-like peptide 1 (GLP-1) promotes glucose homeostasis and enhances β-cell function. GLP-1 receptor agonists (GLP-1 RAs) and dipeptidyl peptidase-4 (DPP-4) inhibitors, which inhibit the physiological inactivation of endogenous GLP-1, are used for the treatment of type 2 di...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
American Diabetes Association
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749354/ |