Combining evidence for association from transmission disequilibrium and case-control studies using single-nucleotide polymorphisms

The aim of the present analysis is to combine evidence for association from the two most commonly used designs in genetic association analysis, the case-control design and the transmission disequilibrium test (TDT) design. The cases here are affected offspring from nuclear families and are used in b...

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Bibliographic Details
Main Authors: Putter, Hein, Houwing-Duistermaat, Jeanine J, Nagelkerke, Nico JD
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866833/