Pirt Functions as an Endogenous Regulator of TRPM8
Pirt is a membrane protein that is specifically expressed in the peripheral nervous system, where it has been shown to increase the sensitivity of the transient receptor potential vanilloid 1 (TRPV1) channel and modulate its role in heat pain. The broad expression of Pirt among dorsal root ganglion...
Main Authors: | Tang, Zongxiang, Kim, Andrew, Masuch, Thorsten, Park, Kyoungsook, Weng, HaoJui, Wetzel, Christian, Dong, Xinzhong |
---|---|
Format: | Online |
Language: | English |
Published: |
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748931/ |
Similar Items
-
Pirt contributes to uterine contraction-induced pain in mice
by: Wang, Changming, et al.
Published: (2015) -
Pirt, a TRPV1 Modulator, Is Required for Histamine-Dependent and -Independent Itch
by: Patel, Kush N., et al.
Published: (2011) -
Targeting of short TRPM8 isoforms induces 4TM-TRPM8-dependent apoptosis in prostate cancer cells
by: Bidaux, Gabriel, et al.
Published: (2016) -
TRPM8 is a neuronal osmosensor that regulates eye blinking in mice
by: Quallo, Talisia, et al.
Published: (2015) -
TRPM8 Puts the Chill on Prostate Cancer
by: Grolez, Guillaume P., et al.
Published: (2016)