Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity

Gastrointestinal nematode parasites infect over 1 billion humans, with little evidence for generation of sterilising immunity. These helminths are highly adapted to their mammalian host, following a developmental program through successive niches, while effectively down-modulating host immune respon...

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Bibliographic Details
Main Authors: Hewitson, James P., Ivens, Al C., Harcus, Yvonne, Filbey, Kara J., McSorley, Henry J., Murray, Janice, Bridgett, Stephen, Ashford, David, Dowle, Adam A., Maizels, Rick M.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744408/