A Lewis acid-promoted Pinner reaction
Carbonitriles and alcohols react in a Lewis acid-promoted Pinner reaction to carboxylic esters. Best results are obtained with two equivalents of trimethylsilyl triflate as Lewis acid. Good yields are achieved with primary alcohols and aliphatic or benzylic carbonitriles, but the straightforward syn...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Beilstein-Institut
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740506/ |