Role of Polycomb Proteins in Regulating HSV-1 Latency

Herpes simplex virus (HSV) establishes a latent infection within sensory neurons of humans. Latency is characterized by the transcriptional repression of lytic genes by the condensation of lytic gene regions into heterochromatin. Recent data suggest that facultative heterochromatin predominates, and...

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Bibliographic Details
Main Authors: Watson, Zachary, Dhummakupt, Adit, Messer, Harald, Phelan, Dane, Bloom, David
Format: Online
Language:English
Published: MDPI 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738959/