The characteristic site-specific reactivation phenotypes of HSV-1 and HSV-2 depend upon the latency-associated transcript region

After replication at sites of initial inoculation, herpes simplex virus type 1 and 2 (HSV-1 and HSV-2) establish lifelong latent infections of the sensory and autonomic neurons of the ganglia serving those sites. Periodically, the virus reactivates from these neurons, and travels centripetally along...

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Bibliographic Details
Format: Online
Language:English
Published: The Rockefeller University Press 1996
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192722/