Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B

To fend off foreign genetic elements, prokaryotes have developed several defense systems. The most recently discovered defense system, CRISPR/Cas, is sequence-specific, adaptive and heritable. The two central components of this system are the Cas proteins and the CRISPR RNA. The latter consists of r...

Full description

Bibliographic Details
Main Authors: Maier, Lisa-Katharina, Lange, Sita J., Stoll, Britta, Haas, Karina A., Fischer, Susan, Fischer, Eike, Duchardt-Ferner, Elke, Wöhnert, Jens, Backofen, Rolf, Marchfelder, Anita
Format: Online
Language:English
Published: Landes Bioscience 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737343/