Engineering a serum-resistant and thermostable vesicular stomatitis virus G glycoprotein for pseudotyping retroviral and lentiviral vectors
Vesicular stomatitis virus G glycoprotein (VSV-G) is the most widely used envelope protein for retroviral and lentiviral vector pseudotyping; however, serum inactivation of VSV-G pseudotyped vectors is a significant challenge for in vivo gene delivery. To address this problem, we conducted directed...
Main Authors: | Hwang, Bum-Yeol, Schaffer, David V. |
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Format: | Online |
Language: | English |
Published: |
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735647/ |
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