Highly Efficient Retrograde Gene Transfer into Motor Neurons by a Lentiviral Vector Pseudotyped with Fusion Glycoprotein

The development of gene therapy techniques to introduce transgenes that promote neuronal survival and protection provides effective therapeutic approaches for neurological and neurodegenerative diseases. Intramuscular injection of adenoviral and adeno-associated viral vectors, as well as lentiviral...

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Bibliographic Details
Main Authors: Hirano, Miyabi, Kato, Shigeki, Kobayashi, Kenta, Okada, Tomoaki, Yaginuma, Hiroyuki, Kobayashi, Kazuto
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782444/