Rapid Global Fitting of Large Fluorescence Lifetime Imaging Microscopy Datasets

Fluorescence lifetime imaging (FLIM) is widely applied to obtain quantitative information from fluorescence signals, particularly using Förster Resonant Energy Transfer (FRET) measurements to map, for example, protein-protein interactions. Extracting FRET efficiencies or population fractions typical...

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Bibliographic Details
Main Authors: Warren, Sean C., Margineanu, Anca, Alibhai, Dominic, Kelly, Douglas J., Talbot, Clifford, Alexandrov, Yuriy, Munro, Ian, Katan, Matilda, Dunsby, Chris, French, Paul M. W.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3734241/