KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions

Zinc finger proteins containing the Kruppel associated box (KRAB-ZFPs) constitute the largest individual family of transcriptional repressors encoded by the genomes of higher organisms. KRAB domain, positioned at the NH2 terminus of the KRAB-ZFPs, interacts with a scaffold protein, KAP-1, which is a...

Full description

Bibliographic Details
Main Authors: Lupo, Angelo, Cesaro, Elena, Montano, Giorgia, Zurlo, Diana, Izzo, Paola, Costanzo, Paola
Format: Online
Language:English
Published: Bentham Science Publishers 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731817/