Interaction between the MTHFR C677T polymorphism and traumatic childhood events predicts depression

Interaction between the MTHFR C677T polymorphism and traumatic childhood events predicts depression

Childhood trauma is associated with the onset and recurrence of major depressive disorder (MDD). The thermolabile T variant of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) is associated with a limited (oxidative) stress defense. Therefore, C677T MTHFR could be a pot...

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Bibliographic Details
Main Authors:	Lok, A, Bockting, C L H, Koeter, M W J, Snieder, H, Assies, J, Mocking, R J T, Vinkers, C H, Kahn, R S, Boks, M P, Schene, A H
Format:	Online
Language:	English
Published:	Nature Publishing Group 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731792/

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