Delivery of Therapeutic AGT shRNA by PEG-Bu for Hypertension Therapy

Gene silencing by RNA interference (RNAi) is a promising approach for gene therapy. However, up to today, it is still a major challenge to find safe and efficient non-viral vectors. Previously, we reported PEI-Bu, a small molecular weight PEI derivative, as an efficient non-viral carrier. However, l...

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Bibliographic Details
Main Authors: Wang, Yu-Qiang, Wang, Fei, Deng, Xiao-Qin, Sheng, Jing, Chen, Shu-Yan, Su, Jing
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716693/