Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Class I histone deacetylases (HDAC1, HDAC2, and HDAC3) are recruited by cognate corepressor proteins into specific transcriptional repression complexes that target HDAC activity to chromatin resulting in chromatin condensation and transcriptional silencing. We previously reported the structure of HD...

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Bibliographic Details
Main Authors: Millard, Christopher J., Watson, Peter J., Celardo, Ivana, Gordiyenko, Yuliya, Cowley, Shaun M., Robinson, Carol V., Fairall, Louise, Schwabe, John W.R.
Format: Online
Language:English
Published: Cell Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710971/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710971/

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