Nuclear hormone receptor co-repressors: Structure and function

► Co-repressors SMRT/NCoR act as “hub proteins”. ► SMRT/NCoR integrate transcription factor and histone modifying enzyme signaling. ► Structures of co-repressor complexes. ► Structural studies provide mechanistic, and potentially therapeutic, insights.

Bibliographic Details
Main Authors: Watson, Peter J., Fairall, Louise, Schwabe, John W.R.
Format: Online
Language:English
Published: North Holland Publishing 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315023/