Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer

With the increasing number of available predictive biomarkers, clinical management of cancer is becoming increasingly reliant on the accurate serial monitoring of tumor genotypes. We tested whether tumor-specific copy number changes can be inferred from the peripheral blood of patients with cancer....

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Bibliographic Details
Main Authors: Heitzer, Ellen, Auer, Martina, Hoffmann, Eva Maria, Pichler, Martin, Gasch, Christin, Ulz, Peter, Lax, Sigurd, Waldispuehl-Geigl, Julie, Mauermann, Oliver, Mohan, Sumitra, Pristauz, Gunda, Lackner, Carolin, Höfler, Gerald, Eisner, Florian, Petru, Edgar, Sill, Heinz, Samonigg, Hellmut, Pantel, Klaus, Riethdorf, Sabine, Bauernhofer, Thomas, Geigl, Jochen B, Speicher, Michael R
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708119/