Guanylate cyclase C signaling: an intestinal secretory pathway where bugs, genes and new drugs intersect

Acute infectious and chronic diarrheal diseases are important public health problems. A recent study by Fiskerstrand and colleagues identified a family with a rare early onset familial diarrhea. By linkage analysis and exon sequencing, the authors identified a heterozygous missense mutation in GUCY2...

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Bibliographic Details
Main Author: Camilleri, Michael
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698531/